Antibacterial triterpenoids from Melia toosendan

نویسندگان

  • Qin Zhu
  • Ligen Lin
  • Chunping Tang
  • Changqiang Ke
  • Yang Ye
چکیده

A new lanostan-type triterpenoid with hydroperoxy group, toosendanin A (1), together with two known triterpenoids, meliastatin 3 (2) and ursolic acid (3), were isolated and identified from the stems of Melia toosendan. The structures of these compounds were elucidated by 1Dand 2D-NMR spectra and other spectroscopic studies. These compounds were assayed for the antibacterial activities against some hospital pathogenic bacteria. Toosendanin A (1) exhibited strong antibacterial activity against K. pneumoniae.

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تاریخ انتشار 2014